Monday, 15 April 2019

Developing GMO Skinap Wound Healing

By Richard Howard


There are ways in the human body in patching up wounds. There are platelets to promote blood clotting on the affected area. They will clump over there to stop further bleeding. Times have seen the development of science and in particular, human biology. One of these developments is the creation of GMO Skinap wound healing.

Said company, Skinap Therapeutics, had developed this medical process. The company itself is known as one of the advanced leaders in biotechnology innovations. Wound healing and tissue regeneration are their areas of expertise as they create medicines and medical devices to better the health and life of patients. They strive to deal with life threatening wounds that cannot be healed and tissue failures that can potentially lead to diseases.

They incorporated the concept of genetically modified organisms or GMOs which has been known for a number of years. They apply the results of this genetic engineering experimentation to their own medical creation. This concept surrounds on the genetic DNA of a host and an intended medium. This is extracted from the host specie and then inserted to the unrelated specie.

In this case, they use animals like maggots as the GMO. They are engineered to secrete a solution called PDGF BB. It means platelet derived growth factor with a BB sub unit. Potent in mitogen, the maggots are placed over the affected area to encourage rapid cell regeneration. However, using them is only allowed in debridement where damaged, dead, and infected tissues are removed from the wound.

They determine if the process is working through clinical validation. It is mostly based on the logic behind the movement of cells during healing. Healthy cells are multiplied which are then migrating towards the wound. They invade the wound beds until it eventually seals.

This behavior of cells are complex, as found by the biological science. Skinap Therapeutics has research teams following and studying their behavior. They found out that these cells are relying on various factors. One of these factors is gene expression where they control and select which genes are expressed in the cell DNA for the creation of functional proteins.

It is the proteins who support cell structure. Biosynthesis, modification and folding are the factors that affect cell behavior. Cells create newer through biosynthesis. It is because some proteins are lost to degradation. Ribosome synthesis then modifies them in order to help them mature. Acquiring a structure in performing their biological function happens as they fold.

Cell communication may be through their environment or with each other. Signals are simultaneously sent and received to trigger a response. Once the signal is received, it will pass through the proteins to change the cell behavior. In this particular case, cells are going to heal the wound until it is sealed.

All these are made possible through the help of a good blood circulation. This helps in determining the healing rate of the wounded area. If a vein is obstructed, it will slow down the blood flow which in turn slows the healing process. There is a possibility of worsening infections in the patient.




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